The Brady lab is developing a way to predict future antibiotic resistance threats by identifying them in nature. This allows proactive design of next generation antibiotics to evade resistance.
Natural products, especially genetically encoded small molecules, have a wide range of functions in biology and have proved very useful in the development of therapeutic agents. Brady’s research centers on the discovery and characterization of new, genetically encoded small molecules from microbial sources, with a special focus on those produced by uncultured soil bacteria, human commensal bacteria, and pathogenic bacteria.
