The Funabiki lab is developing an innovative method, MagIC-Cryo-EM, to rapidly determine high-resolution molecular structures from limited resources. This method will serve as new tool to facilitate structural analysis of diverse pathogen targets for research scientists.
Chromosomes carry core operating programs for life. During mitosis, a full set of chromosomes must be equally transmitted to the offspring of each dividing cell. Failures in this process can result in numerous disorders, such as cancers. Funabiki studies the molecular signatures and mechanisms of chromosome identity and inheritance.